概述（Summary）icon

英文全称

Recombinant Human SNAI1 protein

纯度（Purity）

>90% as determined by SDS-PAGE

内毒素（Endotoxin level）

Please contact with the lab for this information.

蛋白构建（Construction）

A DNA sequence encoding the human SNAI1 (Met1-Arg264) was fused with His tag

Accession #

O95863

表达宿主（Host）

E.coli

种属（Species）

Homo sapiens (Human)

预测分子量（Predicted Molecular Mass）

30.71 kDa

制剂（Formulation）

Supplied as solution form in PBS pH 7.5./ Lyophilized from PBS pH 7.5.

运输方式（Shipping）

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

稳定性&储存（Stability &Storage）

Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.

复溶（Reconstitution）

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

背景（Background）icon

背景介绍

The Snail family transcriptional repressor 1 (SNAI1) is known to promote metastatic phenotypes in renal cell carcinoma (RCC). Targeting the miR-211-5p/SNAI1 signaling pathway may be a novel therapeutic approach for the treatment of RCC metastasis. Given its central role in EMT and tumor metastasis, the cell has evolved multiple levels of regulatory mechanism at transcriptional, post-transcriptional, and post-translational level to regulate SNAI1 expression. SNAI1, a zinc-finger transcription factor, plays an important role in the induction of epithelial-mesenchymal transition (EMT) in various cancers.

分子别名（Alternative Names）

Zinc finger protein SNAI1,Protein snail homolog 1,Protein sna.