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Recombinant Human AhR protein
  • 品牌:chemstan
  • 产地:中国
  • 货号:CSP00379
  • 价格: ¥1280/支
  • 发布日期: 2020-11-04
  • 更新日期: 2024-03-27
产品详请
产地 中国
品牌 chemstan
货号 CSP00379
用途范围 科研实验
纯度 >90%
规格 50ug
是否进口

概述(Summary)icon

英文全称

Recombinant Human AhR protein

纯度(Purity)

>90% as determined by SDS-PAGE

内毒素(Endotoxin level)

Please contact with the lab for this information.

蛋白构建(Construction)

A DNA sequence encoding the human AhR (Val23-Gln273) was fused with His tag

Accession #

P35869

表达宿主(Host)

E.coli

种属(Species)

Homo sapiens (Human)

预测分子量(Predicted Molecular Mass)

28.97 kDa

制剂(Formulation)

Supplied as solution form in PBS pH 7.5./ Lyophilized from PBS pH 7.5.

运输方式(Shipping)

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

稳定性&储存(Stability &Storage)

Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.

复溶(Reconstitution)

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

背景(Background)icon

背景介绍

Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.

分子别名(Alternative Names)

Aryl hydrocarbon receptor,Ah receptor,AhR,Class E basic helix-loop-helix protein 76,bHLHe76.


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