概述（Summary）icon

英文全称

Recombinant Human PTPN6 protein

纯度（Purity）

>90% as determined by SDS-PAGE

内毒素（Endotoxin level）

Please contact with the lab for this information.

蛋白构建（Construction）

A DNA sequence encoding the human PTPN6 (Phe244-Phe515) was fused with His tag

Accession #

P29350

表达宿主（Host）

E.coli

种属（Species）

Homo sapiens (Human)

预测分子量（Predicted Molecular Mass）

30.61 kDa

制剂（Formulation）

Supplied as solution form in PBS pH 7.5./ Lyophilized from PBS pH 7.5.

运输方式（Shipping）

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

稳定性&储存（Stability &Storage）

Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.

复溶（Reconstitution）

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

背景（Background）icon

背景介绍

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

分子别名（Alternative Names）

Tyrosine-protein phosphatase non-receptor type 6,Hematopoietic cell protein-tyrosine phosphatase,Protein-tyrosine phosphatase 1C,PTP-1C,Protein-tyrosine phosphatase SHP-1,SH-PTP1.