CAS编号 | 615258-40-7 |
抗体名 | Denosumab |
用途范围 | 科研实验 |
纯度 | 95% HPLC% |
产地 | 中国 |
品牌 | chemstan |
货号 | CSD00157 |
保存条件 | store at -80°C |
保质期 | -20°C/1 year |
规格 | 100mg |
产品用途 | 科研实验 |
浓度 | 1mg/ml% |
是否进口 | 否 |
货号(Catalog No.)
CSD00157
通用名INN
Denosumab
纯度(Purity)
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer pH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
生物活性
产品描述(Description)
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption markers in patients with a variety of metastatic tumors and is being investigated in multiple clinical trials for the prevention and treatment of bone metastases. Chemically, it consists of 2 heavy and 2 light chains. Each light chain consists of 215 amino acids. Each heavy chain consists of 448 amino acids with 4 intramolecular disulfides. FDA approved on June 1, 2010.
别名(Alternative names)
AMG162
靶点;物种(Specificity target name;species)
TNFSF11/CD254[Homo sapiens]
种类(Species)
Homo sapiens
受体鉴定(Receptor identification)
IgG2-kappa
化学信息
分子量(MV)
144700.00 Da
CAS
615258-40-7
存储条件(Storage)
store at -80°C
Note
For research use only. Not suitable for clinical or therapeutic use.
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