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产品展示
首页 > 产品展厅 > 抗体 Antibody  > 达妥木单抗 (Daratumumab)

达妥木单抗 (Daratumumab)
起批量( 价格
≥1 ¥100元/支
  • 供货能力:100
  • 最低订购量:1支
  • 可销售总数量:100支
  • 建议零销价:100元/支
  • 发布日期: 2020-12-14
  • 更新日期: 2020-12-14
产品详细说明
抗体名: Daratumumab 浓度: 1mg/ml %
靶点: 宿主:
用途范围: 科研实验 应用范围:
纯度: 95% HPLC % 产地: 中国
品牌: chemstan 货号: CSD00199
产品用途: 科研实验 亚型:
是否单克隆: 免疫原:
保质期: -20°C/1 year CAS编号: 945721-28-8
标记物: 规格: 100mg
抗原来源: 适应物种:
克隆性: 标识物:
形态: 保存条件: store at -80°C
是否进口:

货号(Catalog No.)icon

CSD00199

通用名INNicon

Daratumumab

纯度(Purity)icon

>95%

浓度( Concentration)icon

1mg/ml

Formulationicon

PBS buffer pH7.5

Sourceicon

CHO cells

内毒素(Endotoxin level)icon

Please contact with the lab for this information.

生物活性icon

产品描述(Description)

Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells.

别名(Alternative names)

HuMax-CD38

靶点;物种(Specificity target name;species)

CD38[Homo sapiens]

活性研究(体外/体内研究)(Activity in vitro)

Daratumumab was studied in a series of in vitro assays and was found to induce CDC in freshly isolated MM cells obtained from the bone marrow of 13 previously untreated or relapsed MM patients. Furthermore, daratumumab triggered antibody-dependent cell-mediated cytotoxicity (ADCC) in CD38-expressing MM cell lines in peripheral blood mononuclear cells (PBMCs) enriched for NK cells, as well as in patient MM cells in the presence of both autologous and allogeneic effector cells.

种类(Species)

Homo sapiens

受体鉴定(Receptor identification)

IgG1-kappa

化学信息icon

分子量(MV)

148000.00 Da

CAS

945721-28-8

存储条件(Storage)

store at -80°C



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