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Isolimonexic acid
  • 品牌:chemstan
  • 产地:中国
  • 货号:CS-N8405
  • cas:73904-93-5
  • 价格: ¥4800/mg
  • 发布日期: 2020-12-29
  • 更新日期: 2024-04-20
产品详请
产地 中国
品牌 chemstan
货号 CS-N8405
用途范围 科研
英文名称 Isolimonexic acid
纯度 %
CAS编号 73904-93-5
规格 100 mg
分子式 C??H??O??
是否进口
Description

Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties[1] .

IC50 & Target

IC50: 25.60 μM (aromatase)[1]

In Vitro

Isolimonexic acid (200 μM; 72 hours) exhibits cytotoxicity on MCF-7 cells and shows no cytotoxicity against the MDA-MB-231 cell lines[1] .
Isolimonexic acid (50 μg/ml; 48, 96 and 144 hours) exhibits cell growth inhibition of Panc-28 cells in a time-dependent manner.And it percent inhibition comparison to control cells are 21%, 68%, and 90.58% at 48, 72, and 144 h, respectively[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

502.51

Formula

C??H??O??

CAS No.

73904-93-5

SMILES

C[C@]12[C@]34[C@](C(O[C@](C5=CC(OC5=O)O)([H])[C@@]4(CC[C@]1([H])[C@]67[C@@](C(C)(O[C@@]6([H])CC(OC7)=O)C)([H])CC2=O)C)=O)([H])O3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • [1]. Jinhee Kim, et al. Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct. 2013 Feb;4(2):258-65.

    [2]. Jaiprakash R Patil, et al.Bioactive compounds from Mexican lime ( Citrus aurantifolia ) juice induce apoptosis in human pancreatic cells. J Agric Food Chem. 2009 Nov 25;57(22):10933-42.


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