Spebrutinib is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity.

靶点： BRK; BTK; c-Src; Lyn; Yes;

Spebrutinib is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity.

司培替尼用途：

AVL-292 是一种有效的 Btk 激酶活性抑制剂，IC50<0.5 nM，Kinact/Ki 为 7.69×104 M-1s-1s。