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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 96206-92-7 |
| 是否进口 | 否 |
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Fields of Application :
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM.
| CAS Number: | 96206-92-7 |
| Purity: | >98.5% |
| Molecular Weight: | 193.24 |
| Molecular Formula: | C14H11N |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | N/A |
| Chemical Name: | 2-methyl-6-(2-phenylethynyl)pyridine |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
MPEP is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. For the detailed information about the solubility of MPEP in water, the solubility of MPEP in DMSO, the solubility of MPEP in PBS buffer, the animal experiment（test） of MPEP,the in vivo,in vitro and clinical trial test of MPEP,the cell experiment（test） of MPEP,the IC50, EC50 and Affinity of MPEP.
References:
C(C)1=NC(C#CC2=CC=CC=C2)=CC=C1
