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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 184025-18-1 |
| 是否进口 | 否 |
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Fields of Application :
Ciproxifan is an antagonists of H3-type histamine receptors.
| CAS Number: | 184025-18-1 |
| Purity: | >98% |
| Molecular Weight: | 306.14 |
| Molecular Formula: | C15H9Cl2NO2 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | FUB359 |
| Chemical Name: | 1H-Indole-2,3-dione, 1-[(3,4-dichlorophenyl)methyl]- |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Ciproxifan, Antagonists of H3-type histamine receptors exhibit cognitive-enhancing properties in various memory paradigms as well as evidence of antipsychotic activity in normal animals.Ciproxifan is an extremely potent histamine H3 inverse agonist/antagonist.Ciproxifan produces wakefulness and attentiveness in animal studies, and produced cognitive enhancing effects without prominent stimulant effects at relatively low levels of receptor occupancy, and pronounced wakefulness at higher doses.It has there Fore been proposed as a potential treatment For sleep disorders such as narcolepsy and to improve vigilance in old age, particularly in the treatment of conditions such as Alzheimer's disease.It also potentiated the effects of antipsychotic drugs, and has been suggested as an adjuvant treatment For schizophrenia. For the detailed information about the solubility of Ciproxifan (FUB-359) in water, the solubility of Ciproxifan (FUB-359) in DMSO, the solubility of Ciproxifan (FUB-359) in PBS buffer, the animal experiment（test） of Ciproxifan (FUB-359),the in vivo,in vitro and clinical trial test of Ciproxifan (FUB-359),the cell experiment（test） of Ciproxifan (FUB-359),the IC50, EC50 and Affinity of Ciproxifan (FUB-359).
References:
C1CC1C(=O)C2=CC=C(C=C2)OCCCC3=CN=CN3
