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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 10537-47-0 |
| 是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体，主打中药对照品/标准品/天然植物有效单体，小分子化合物库，药物杂质。所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。
Fields of Application :
AG-17 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 460 μM in the human epidermoid carcinoma cell line A431.
| CAS Number: | 10537-47-0 |
| Purity: | >98% |
| Molecular Weight: | 282.38 |
| Molecular Formula: | C18H22N2O |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | Tyrphostin 9，Malonoben，Tyrphostin AG-17，SF 6847，GCP 5126，RG-50872，NSC 242557 |
| Chemical Name: | 2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-propanedinitrile |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Tyrphostin 9 is a synthetic inhibitor of protein tyrosine kinase (PTK) that displays characteristics of a potent reversible inhibitor of platelet-derived growth factor (PDGF)-induced mitogenesis via inhibition of tyrosine kinase activity of the PDGFR (PDGF receptor) and other signaling cascades. These studies suggest that Tyrphostin 9 could potentially be used to inhibit cell proliferations which depend on protein tyrosine kinase for replication. This compound was also reported to inhibit actin ring formation and bone resorption in murine osteoclasts. Tyrphostin A9 is a calcium channel protein inhibitor of Calcium Channel Protein (calcium release-activated calcium (CRAC) channels) .
References:
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