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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 127191-97-3 |
| 是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体，主打中药对照品/标准品/天然植物有效单体，小分子化合物库，药物杂质。所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。
| 常用名 | KN-62 | 英文名 | KN-62 |
|---|---|---|---|
| CAS号 | 127191-97-3 | 分子量 | 721.844 |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 964.7±75.0 °C at 760 mmHg |
| 分子式 | C38H35N5O6S2 | 熔点 | 92-94°C |
| MSDS | 美版 | 闪点 | 537.3±37.1 °C |
KN-62 是一种有效的选择性的钙调蛋白依赖性蛋白激酶 II (CaMK-II)抑制剂，IC50 为 0.9 μM，在HEK293 细胞中，KN-62 也非竞争性拮抗P2X7 受体，IC50 约为 15 nM。
Fields of Application :
KN-62 is a sective, cell-permeable inhibitor of CaM kinase II (IC50 = 0.9 μM).
| CAS Number: | 127191-97-3 |
| Purity: | >98% |
| Molecular Weight: | 721.84 |
| Molecular Formula: | C38H35N5O6S2 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | KN 62, KN62 |
| Chemical Name: | |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Binds directly to the calmodulin binding site of the enzyme. Potent non-competitive antagonist at the P2X7 receptor (IC50 = 15 nM). For the detailed information about the solubility of KN-62 in water, the solubility of KN-62 in DMSO, the solubility of KN-62 in PBS buffer, the animal experiment（test） of KN-62,the in vivo,in vitro and clinical trial test of KN-62,the cell experiment（test） of KN-62,the IC50, EC50 and Affinity of KN-62, please contact DC Chemicals.
