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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 112522-64-2 |
| 是否进口 | 否 |
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| 常用名 | 4-乙酰氨基-N-(2'-氨基苯基)-苯甲酰胺 | 英文名 | CI-994 |
|---|---|---|---|
| CAS号 | 112522-64-2 | 分子量 | 269.298 |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 450.6±30.0 °C at 760 mmHg |
| 分子式 | C15H15N3O2 | 熔点 | N/A |
| MSDS | 中文版 美版 | 闪点 | 226.3±24.6 °C |
CI-994 (Tacedinaline)是组蛋白脱乙酰酶(HDAC)的抑制剂，抑制重组HDAC 1, 2 and 3的 IC50 值分别为0.9, 0.9, 1.2 μM.
Fields of Application :
CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 μM.
| CAS Number: | 112522-64-2 |
| Purity: | >98% |
| Molecular Weight: | 269.3 |
| Molecular Formula: | 112522-64-2 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | PD-123654,CI-994,PD123654 |
| Chemical Name: | Benzamide, 4-(acetylamino)-N-(2-aminophenyl)- |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Description of Tacedinaline: Tacedinaline, also known as CI-944, is an orally bioavailable substituted benzamide derivative with potential antineoplastic activity. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) For the detailed information about the solubility of CI994 (Tacedinaline) in water, the solubility of CI994 (Tacedinaline) in DMSO, the solubility of CI994 (Tacedinaline) in PBS buffer, the animal experiment（test） of CI994 (Tacedinaline), the in vivo,in vitro and clinical trial test of CI994 (Tacedinaline), the cell experiment（test） of CI994 (Tacedinaline), the IC50, EC50 and Affinity of CI994 (Tacedinaline) , please contact DC Chemicals.
