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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 944261-79-4 |
| 是否进口 | 否 |
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| 常用名 | A-803467 | 英文名 | A-803467 |
|---|---|---|---|
| CAS号 | 944261-79-4 | 分子量 | 357.788 |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 450.6±45.0 °C at 760 mmHg |
| 分子式 | C19H16ClNO4 | 熔点 | 128-130?C |
| MSDS | 中文版 美版 | 闪点 | 226.3±28.7 °C |
A 803467是Nav1.8钠离子通道阻断剂，IC50为8 nM，比对Nav1.2，1.3，1.5和1.7的抑制性高100倍。
Fields of Application :
A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM.
| CAS Number: | 944261-79-4 |
| Purity: | >98% |
| Molecular Weight: | 357.79 |
| Molecular Formula: | C19H16ClNO4 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | A803467 |
| Chemical Name: | 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
A-803467 is a selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM For hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Antinociceptive; potently attenuates mechanical allodynia in two models of neuropathic pain following i.p. administration. For the detailed information about the solubility of A-803467 in water, the solubility of A-803467 in DMSO, the solubility of A-803467 in PBS buffer, the animal experiment（test） of A-803467,the in vivo,in vitro and clinical trial test of A-803467,the cell experiment（test） of A-803467,the IC50, EC50 and Affinity of A-803467, please contact DC Chemicals.
