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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 265129-71-3 |
| 是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体，主打中药对照品/标准品/天然植物有效单体，小分子化合物库，药物杂质。所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。
| 常用名 | 2-[[4-[2-[[环己基氨基)羰基](4-环己基丁基)氨基]乙基]苯基]硫基]-2-甲基丙酸 | 英文名 | GW-7647 |
|---|---|---|---|
| CAS号 | 265129-71-3 | 分子量 | 502.752 |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 693.9±55.0 °C at 760 mmHg |
| 分子式 | C29H46N2O3S | 熔点 | N/A |
| MSDS | 中文版 美版 | 闪点 | 373.5±31.5 °C |
GW7647 是一种有效的 PPARα 激动剂，对人 PPARα,PPARγ 和 PPARδ 的 EC50 值分别为 6 nM, 1.1 μM 和 6.2 μM。
Fields of Application :
GW 7647 is a potent PPARα agonist with 200-fold selectivity over PPARγ and PPARδ.
| CAS Number: | 265129-71-3 |
| Purity: | >98% |
| Molecular Weight: | 502.75 |
| Molecular Formula: | C29H46N2O3S |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | GW7647, GW 7647 |
| Chemical Name: | |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
GW 7647 is a potent PPARα agonist with 200-fold selectivity over PPARγ and PPARδ. This compound has also been found to cause an up-regulation of β-oxidation gene expression and an increase in palmitate oxidation. Additionally, glycolysis is strongly reduced at transcriptional levels by GW 7647 leading to a decrease in lactate and pyruvate production. Furthermore, this agent displays the ability to decrease glucose oxidation and inhibit lipogenesis and triglyceride esterification. For the detailed information about the solubility of GW-7647 in water, the solubility of GW-7647 in DMSO, the solubility of GW-7647 in PBS buffer, the animal experiment（test） of GW-7647,the in vivo,in vitro and clinical trial test of GW-7647,the cell experiment（test） of GW-7647,the IC50, EC50 and Affinity of GW-7647, please contact DC Chemicals.
