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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 22978-25-2 |
| 是否进口 | 否 |
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| 常用名 | 2-氯-5-硝基-N-苯基苯酰胺 | 英文名 | GW9662 |
|---|---|---|---|
| CAS号 | 22978-25-2 | 分子量 | 276.675 |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 360.9±32.0 °C at 760 mmHg |
| 分子式 | C13H9ClN2O3 | 熔点 | 171-175 °C(lit.) |
| MSDS | 中文版 美版 | 闪点 | 172.0±25.1 °C |
GW9662是有效，选择性的 PPARγ 拮抗剂，IC50值为3.3 nM，比PPARα和PPARδ的选择性高10倍和1000倍。
Fields of Application :
GW9662 is a selective PPAR antagonist, inhibiting PPARγ, PPARα and PPARδ with IC50 of 3.3 nM, 32 nM and 2 μM, respectively.
| CAS Number: | 22978-25-2 |
| Purity: | >98% |
| Molecular Weight: | 276.68 |
| Molecular Formula: | C13H9ClN2O3 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | GW9662, GW 9662 |
| Chemical Name: | Benzamide, 2-chloro-5-nitro-N-phenyl- |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
GW9662 is a potent, irreversible and selective PPARgamma antagonist, which prevented activation of PPARgamma and inhibited growth of human mammary tumour cell lines. For the detailed information about the solubility of GW-9662 in water, the solubility of GW-9662 in DMSO, the solubility of GW-9662 in PBS buffer, the animal experiment（test） of GW-9662,the in vivo,in vitro and clinical trial test of GW-9662,the cell experiment（test） of GW-9662,the IC50, EC50 and Affinity of GW-9662, please contact DC Chemicals.
