|
| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 152121-30-7 |
| 是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体，主打中药对照品/标准品/天然植物有效单体，小分子化合物库，药物杂质。所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。
| 常用名 | 4-(4-氟苯基)-2-(4-羟基苯基)-5-(4-吡啶基)-1H-咪唑 | 英文名 | SB202190 |
|---|---|---|---|
| CAS号 | 152121-30-7 | 分子量 | 331.343 |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 565.7±50.0 °C at 760 mmHg |
| 分子式 | C20H14FN3O | 熔点 | 240-243℃ |
| MSDS | 美版 | 闪点 | 295.9±30.1 °C |
SB 202190 抑制 p38 和 p38β2，IC50 分别为 50 nM 和 100 nM。
Fields of Application :
SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway.
| CAS Number: | 152121-30-7 |
| Purity: | >98% |
| Molecular Weight: | 331.34 |
| Molecular Formula: | C20H14N3OF |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | SB-202190, SB 202190 |
| Chemical Name: | 4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway. The compound inhibits the iso Forms p38α and p38β. SB 202190 has displayed the ability to activate CPP32-like caspases and induce apoptosis. Research demonstrates that when one residue of ERK2, a related p38 not inhibited by pyridinyl imidazoles, is changed it allows SB 202190 to bind. Studies have revealed that SB 202190 can improve leukemia cell growth by activating MEK/MAPK, as well as phosphorylate and activate MLK3. For the detailed information about the solubility of SB 202190 (FHPI) in water, the solubility of SB 202190 (FHPI) in DMSO, the solubility of SB 202190 (FHPI) in PBS buffer, the animal experiment（test） of SB 202190 (FHPI), the in vivo,in vitro and clinical trial test of SB 202190 (FHPI), the cell experiment（test） of SB 202190 (FHPI), the IC50, EC50 and Affinity of SB 202190 (FHPI) , please contact DC Chemicals.
