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Fields of Application : 
Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.

Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)

Note: Products for research use only, not for human use

Description:
Description of cyclosporine: cyclosporine is a natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) For the detailed information about the solubility of Cyclosporin A in water, the solubility of Cyclosporin A in DMSO, the solubility of Cyclosporin A in PBS buffer, the animal experiment（test） of Cyclosporin A,the in vivo,in vitro and clinical trial test of Cyclosporin A,the cell experiment（test） of Cyclosporin A,the IC50, EC50 and Affinity of Cyclosporin A.

References: 
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