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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 121032-29-9 |
| 是否进口 | 否 |
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Fields of Application :
Nelarabine (Arranon, 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
| CAS Number: | 121032-29-9 |
| Purity: | 99% |
| Molecular Weight: | 297.27 |
| Molecular Formula: | C11H15N5O5 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | Arranon |
| Chemical Name: | |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
ARRANON (nelarabine) is a pro-drug of the cytotoxic deoxyguanosine analogue, 9-β-D-arabinofuranosylguanine (ara-G). The chemical name For nelarabine is 2-amino-9-β-D-arabinofuranosyl-6-methoxy-9H-purine. It has the molecular Formula C11H15N5O5 and a molecular weight of 297.27. Nelarabine is slightly soluble to soluble in water and melts with decomposition between 209° and 217° C. ARRANON Injection is supplied as a clear, colorless, sterile solution in glass vials. Each vial contains 250 mg of nelarabine (5 mg nelarabine per mL) and the inactive ingredient sodium chloride (4.5 mg per mL) in 50 mL Water For Injection, USP. ARRANON is intended For intravenous infusion. Hydrochloric acid and sodium hydroxide may have been used to adjust the pH. The solution pH ranges from 5.0 to 7.0. For the detailed information about the solubility of Nelarabine in water, the solubility of Nelarabine in DMSO, the solubility of Nelarabine in PBS buffer, the animal experiment（test） of Nelarabine,the in vivo,in vitro and clinical trial test of Nelarabine,the cell experiment（test） of Nelarabine,the IC50, EC50 and Affinity of Nelarabine.
References:
O[C@@H]([C@@H]1O)[C@@H](O[C@@H]1CO)N(C=N2)C3=C2C(OC)=NC(N)=N3
