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产地 | 中国 |
品牌 | Chemstan |
货号 | LC-01 |
用途 | 中间体 |
包装规格 | 20mg |
纯度 | 98%% |
CAS编号 | 444731-52-6 |
是否进口 | 否 |
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Fields of Application :
Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit.
CAS Number: | 444731-52-6 |
Purity: | 99% |
Molecular Weight: | 437.52 |
Molecular Formula: | C21H23N7O2S |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
Synonyms: | Votrient |
Chemical Name: | 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide |
Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Pazopanib hydrochloride is an approved drug, is the hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). For the detailed information about the solubility of Pazopanib in water, the solubility of Pazopanib in DMSO, the solubility of Pazopanib in PBS buffer, the animal experiment(test) of Pazopanib,the in vivo,in vitro and clinical trial test of Pazopanib,the cell experiment(test) of Pazopanib,the IC50, EC50 and Affinity of Pazopanib.
References:
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