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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 957054-30-7 |
| 是否进口 | 否 |
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Fields of Application :
GDC-0941 is a potent inhibitor of PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ with IC50 of 3 nM, 33 nM, 3 nM and 75 nM, respectively.
| CAS Number: | 957054-30-7 |
| Purity: | 99% |
| Molecular Weight: | 513.64 |
| Molecular Formula: | C23H27N7O3S2 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | GDC-0941,GDC 0941 |
| Chemical Name: | 2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidine |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
A potent, selective inhibitor of class I PI3 kinase (PI3K) with IC50 values (nM) of 3, 33, 3, 75, 1230 and 580 For p110 α, β, δ and γ iso Forms, DNA-PK and mTOR, respectively, exhibiting excellent pharmacokinetic properties in all animal models. For the detailed information about the solubility of GDC0941 in water, the solubility of GDC0941 in DMSO, the solubility of GDC0941 in PBS buffer, the animal experiment（test） of GDC0941,the in vivo,in vitro and clinical trial test of GDC0941,the cell experiment（test） of GDC0941,the IC50, EC50 and Affinity of GDC0941.
References:
CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
