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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 439081-18-2 |
| 是否进口 | 否 |
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Fields of Application :
BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
| CAS Number: | 439081-18-2 |
| Purity: | 99% |
| Molecular Weight: | 485.94 |
| Molecular Formula: | C24H25ClFN5O3 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | Afatinib, BIBW2992,BIBW-2292 |
| Chemical Name: | (S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
For the detailed information about the solubility of Afatinib (BIBW2992) in water, the solubility of Afatinib (BIBW2992) in DMSO, the solubility of Afatinib (BIBW2992) in PBS buffer, the animal experiment（test） of Afatinib (BIBW2992),the in vivo,in vitro and clinical trial test of Afatinib (BIBW2992),the cell experiment（test） of Afatinib (BIBW2992),the IC50, EC50 and Affinity of Afatinib (BIBW2992).
References:
CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4
