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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 129453-61-8 |
| 是否进口 | 否 |
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Fields of Application :
Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.094 nM.
| CAS Number: | 129453-61-8 |
| Purity: | >99% |
| Molecular Weight: | 606.77 |
| Molecular Formula: | C32H47F5O3S |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | N/A |
| Chemical Name: | |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Description of Fulvestrant: Fulvestrant is a synthetic estrogen receptor antagonist. Unlike tamoxifen (which has partial agonist effects) and the aromatase inhibitors (which reduce the estrogen available to tumor cells), fulvestrant binds competitively to estrogen receptors in breast cancer cells, resulting in estrogen receptor de Formation and decreased estrogen binding. In vitro studies indicate that fulvestrant reversibly inhibits the growth of tamoxifen-resistant, estrogen-sensitive, human breast cancer cell lines. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) For the detailed information about the solubility of Fulvestrant in water, the solubility of Fulvestrant in DMSO, the solubility of Fulvestrant in PBS buffer, the animal experiment（test） of Fulvestrant, the in vivo,in vitro and clinical trial test of Fulvestrant, the cell experiment（test） of Fulvestrant, the IC50, EC50 and Affinity of Fulvestrant .
References:
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F
