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产地 | 中国 |
品牌 | Chemstan |
货号 | LC-01 |
用途 | 中间体 |
包装规格 | 20mg |
纯度 | 98%% |
CAS编号 | 1320288-19-4 |
是否进口 | 否 |
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Fields of Application :
UNC-0631 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity.
CAS Number: | 1320288-19-4 |
Purity: | >98% |
Molecular Weight: | 635.93 |
Molecular Formula: | C37H61N7O2 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
Synonyms: | UNC0631; UNC 0631; UNC-0631 |
Chemical Name: | N-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine |
Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
UNC-0631 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity. Protein lysine methyltransferase G9a plays key roles in the transcriptional repression of a variety of genes via dimethylation of lysine 9 on histone H3 (H3K9me2) of chromatin as well as dimethylation of nonhistone proteins including tumor suppressor p53.For the detailed information of UNC0631, the solubility of UNC0631 in water, the solubility of UNC0631 in DMSO, the solubility of UNC0631 in PBS buffer, the animal experiment (test) of UNC0631, the cell expriment (test) of UNC0631, the in vivo, in vitro and clinical trial test of UNC0631, the EC50, IC50,and Affinity of UNC0631.
References:
CC(C)N1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5CCCCC5)OC)OCCCN6CCCCC6