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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 873697-71-3 |
| 是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体，主打中药对照品/标准品/天然植物有效单体，小分子化合物库，药物杂质。所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。
| 常用名 | 4-[[2-氟-3-[N'-(6-甲基吡啶-3-基)脲基]苯基]甲基]哌嗪-1-羧酸甲酯 | 英文名 | Omecamtiv mecarbil |
|---|---|---|---|
| CAS号 | 873697-71-3 | 分子量 | 401.435 |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 456.8±45.0 °C at 760 mmHg |
| 分子式 | C20H24FN5O3 | 熔点 | 180℃ |
| MSDS | N/A | 闪点 | 230.1±28.7 °C |
Omecamtiv mecarbil 是具有选择性的 myosin 激活剂，常用于治疗心血管疾病。
Fields of Application :
Omecamtivmecarbil (CK-1827452) is a specific cardiac myosinactivator and a clinical drug for left ventricular systolic heart failure.
| CAS Number: | 873697-71-3 |
| Purity: | >98% |
| Molecular Weight: | 401.43 |
| Molecular Formula: | C20H24FN5O3 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | CK-1827452, CK1827452,CK 1827452 |
| Chemical Name: | |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Omecamtiv mecarbil (CK-1827452; CK1827452) is a selective sarcomere-directed cardiac myosin activator with an E50 of 0.6 μM. Omecamtiv mecarbil, a novel cardiac muscle myosin activator, is currently the subject of a Phase II clinical trials program. This program was designed to evaluate the safety, tolerability, pharmacodynamics and pharmacokinetic profile of both intravenous and oral Formulations of omecamtiv mecarbil For the potential treatment of heart failure across the continuum of care, in both hospital and outpatient settings. Omecamtiv mecarbil (CK-1827452; CK1827452 ) is useful For treatment of heart failure.For the detailed information of Omecamtiv mecarbil (CK-1827452), the solubility of Omecamtiv mecarbil (CK-1827452) in water, the solubility of Omecamtiv mecarbil (CK-1827452) in DMSO, the solubility of Omecamtiv mecarbil (CK-1827452) in PBS buffer, the animal experiment (test) of Omecamtiv mecarbil (CK-1827452), the cell expriment (test) of Omecamtiv mecarbil (CK-1827452), the in vivo, in vitro and clinical trial test of Omecamtiv mecarbil (CK-1827452), the EC50, IC50,and Affinity of Omecamtiv mecarbil (CK-1827452), Please contact DC Chemicals.
