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产地 | 中国 |
品牌 | Chemstan |
货号 | LC-01 |
用途 | 中间体 |
包装规格 | 20mg |
纯度 | 98%% |
CAS编号 | 376348-65-1 |
是否进口 | 否 |
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常用名 | 马拉维若 | 英文名 | Maraviroc |
---|---|---|---|
CAS号 | 376348-65-1 | 分子量 | 513.666 |
密度 | 1.3±0.1 g/cm3 | 沸点 | N/A |
分子式 | C29H41F2N5O | 熔点 | 79-81oC |
MSDS | 中文版 美版 | 闪点 | N/A |
Maraviroc 是一种选择性的 CCR5 拮抗剂,抑制 MIP-1α (IC50,3.3 nM),MIP-1β (IC50,7.2 nM) 和 RANTES (IC50,5.2 nM) 结合到表达 CCR5 的 HEK-293 细胞膜。
Fields of Application :
Maraviroc (Selzentry, UK-427857, Celsentri) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM, respectively.
CAS Number: | 376348-65-1 |
Purity: | >98% |
Molecular Weight: | 513.67 |
Molecular Formula: | C29H41F2N5O |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
Synonyms: | UK-427857, Celsentri |
Chemical Name: | 4,4-difluoro-N-((S)-3-(3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)cyclohexanecarboxamide |
Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
For the detailed information about the solubility of Maraviroc in water, the solubility of Maraviroc in DMSO, the solubility of Maraviroc in PBS buffer, the animal experiment(test) of Maraviroc, the in vivo,in vitro and clinical trial test of Maraviroc, the cell experiment(test) of Maraviroc, the IC50, EC50 and Affinity of Maraviroc , please contact DC Chemicals.For the detailed information of Maraviroc, the solubility of Maraviroc in water, the solubility of Maraviroc in DMSO, the solubility of Maraviroc in PBS buffer, the animal experiment (test) of Maraviroc, the cell expriment (test) of Maraviroc, the in vivo, in vitro and clinical trial test of Maraviroc, the EC50, IC50,and Affinity of Maraviroc, Please contact DC Chemicals.