|
| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 183322-45-4 |
| 是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体，主打中药对照品/标准品/天然植物有效单体，小分子化合物库，药物杂质。所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。
| 常用名 | 6,7-二甲氧基-4-[N-(3-溴苯基)氨基]喹唑啉盐酸盐 | 英文名 | PD153035 Hydrochloride |
|---|---|---|---|
| CAS号 | 183322-45-4 | 分子量 | 396.666 |
| 密度 | N/A | 沸点 | 472.1oC at 760 mmHg |
| 分子式 | C16H15BrClN3O2 | 熔点 | 265°C(lit.) |
| MSDS | 中文版 美版 | 闪点 | 239.3oC |
PD153035 (ZM 252868;AG 1517;Tyrphostin AG 1517;SU 5271) 是有效地 EGFR 抑制剂， Ki 和 IC50 值分别为6和25 pM。
Fields of Application :
PD153035 is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src.
| CAS Number: | 183322-45-4 |
| Purity: | >98% |
| Molecular Weight: | 396.67 |
| Molecular Formula: | C16H14BrN3O2.HCl |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | PD 153035,SU 5271, AG-1517,PD-153035,SU5271, AG 1517 |
| Chemical Name: | |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
PD153035 HCl is an extremely potent inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase, . Inhibits other purified tyrosine kinases only at micromolar or higher concentrations.For the detailed information of PD153035 HCl (SU-5271, AG1517), the solubility of PD153035 HCl (SU-5271, AG1517) in water, the solubility of PD153035 HCl (SU-5271, AG1517) in DMSO, the solubility of PD153035 HCl (SU-5271, AG1517) in PBS buffer, the animal experiment (test) of PD153035 HCl (SU-5271, AG1517), the cell expriment (test) of PD153035 HCl (SU-5271, AG1517), the in vivo, in vitro and clinical trial test of PD153035 HCl (SU-5271, AG1517), the EC50, IC50,and Affinity of PD153035 HCl (SU-5271, AG1517), Please contact DC Chemicals.
