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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 839707-37-8 |
| 是否进口 | 否 |
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Fields of Application :
SC1(Pluripotin) is a sustainer of mES self-renewal and ERK 1 inhibitor
| CAS Number: | 839707-37-8 |
| Purity: | >98% |
| Molecular Weight: | 550.5 |
| Molecular Formula: | C27H25F3N8O2 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | |
| Chemical Name: | N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
SC1 is a small molecule shown to sustain self-renewal of mouse embryonic stem (mES) cells. In order to maintain embryonic stem cells in an undifferentiated state, it is typically necessary to use a combination of feeder cells, leukemia inhibitor factor (LIF) and bone morphogenic protein (BMP); SC1 (Pluripotin) allows For stem cell propagation in the absence of these factors. The activity of SC1 is mediated by Ras signaling which promotes self-renewal, and inhibition of ERK blocks differentiation.For the detailed information of SC1 (Pluripotin), the solubility of SC1 (Pluripotin) in water, the solubility of SC1 (Pluripotin) in DMSO, the solubility of SC1 (Pluripotin) in PBS buffer, the animal experiment (test) of SC1 (Pluripotin), the cell expriment (test) of SC1 (Pluripotin), the in vivo, in vitro and clinical trial test of SC1 (Pluripotin), the EC50, IC50,and Affinity of SC1 (Pluripotin).
References:
CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C
