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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 863329-66-2 |
| 是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体，主打中药对照品/标准品/天然植物有效单体，小分子化合物库，药物杂质。所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。
| 常用名 | (2'R)-2'-脱氧-2'-氟-2'-甲基脲苷 | 英文名 | (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine |
|---|---|---|---|
| CAS号 | 863329-66-2 | 分子量 | 260.219 |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | N/A |
| 分子式 | C10H13FN2O5 | 熔点 | 237-238℃ |
| MSDS | N/A | 闪点 | N/A |
PSI-6206 是 PSI-6130 的脱氨衍生物，PSI-6130 是一种有效的选择性 HCV NS5B 聚合酶抑制剂。PSI-6206 低效抑制HCV复制，EC90 为 >100 μM。
Fields of Application :
PSI-6206 is a selective inhibitor of hepatitis C virus (HCV).
| CAS Number: | 863329-66-2 |
| Purity: | >98% |
| Molecular Weight: | 260.22 |
| Molecular Formula: | C10H13FN2O5 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | PSI-6206, RO-2433, PSI6206, RO2433 |
| Chemical Name: | N/A |
| Storage: | 2 years -20°C powder,2 weeks 4°C in DMSO,6 months -80°C in DMSO |
Note: Products for research use only, not for human use
Description:
PSI-6206 (RO2433) is the unphosphorylated parent compound of triphosphate analog PSI-7409, which is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase. The monophosphate Form of PSI-6206 was shown to be metabolized in primary human hepatocytes to its triphosphate analog PSI-7409. Furthermore, the phosphoramidate prodrug of PSI-6206 monophosphate, PSI-7851, was developed. Alternatively, PSI-6130, an aminated analog of PSI-6206 monophosphate, was also developed. (1,2,3)For the detailed information of PSI6206, the solubility of PSI6206 in water, the solubility of PSI6206 in DMSO, the solubility of PSI6206 in PBS buffer, the animal experiment (test) of PSI6206, the cell expriment (test) of PSI6206, the in vivo, in vitro and clinical trial test of PSI6206, the EC50, IC50,and Affinity of PSI6206, Please contact DC Chemicals.
