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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 882663-88-9 |
| 是否进口 | 否 |
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Fields of Application :
AMG-47a is a potent inhibitor of Lck and T cell proliferation; exhibits anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.
| CAS Number: | 882663-88-9 |
| Purity: | >98% |
| Molecular Weight: | 535.56 |
| Molecular Formula: | C29H28F3N5O2 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | AMG 47，AMG-47，AMG47 |
| Chemical Name: | 4-methyl-3-[2-(2-morpholin-4-ylethylamino)quinazolin-6-yl]-N-[3-(trifluoromethyl)phenyl]benzamide |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.For the detailed information of AMG-47a, the solubility of AMG-47a in water, the solubility of AMG-47a in DMSO, the solubility of AMG-47a in PBS buffer, the animal experiment (test) of AMG-47a, the cell expriment (test) of AMG-47a, the in vivo, in vitro and clinical trial test of AMG-47a, the EC50, IC50,and Affinity of AMG-47a.
References:
CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=CN=C(N=C4C=C3)NCCN5CCOCC5
