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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 487021-52-3 |
| 是否进口 | 否 |
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Fields of Application :
AR-A014418 is a selective and effective GSK3β inhibitor with an IC 50 value of 104 +/- 27 nM; no significant inhibition on 26 other kinases.
| CAS Number: | 487021-52-3 |
| Purity: | >98% |
| Molecular Weight: | 308.31308 |
| Molecular Formula: | C12H12N4O4S |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | AR-AO 14418; AR 0133418; AR 014418; GSK 3β inhibitor |
| Chemical Name: | 1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Cell-permeable. A selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC?? = 104 nM). Inhibition is competitive with respect to ATP (Ki = 38nM). Exhibits specificity For GSK-3 over cdk2 and cdk5 (IC?? values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices.For the detailed information of AR-A014418, the solubility of AR-A014418 in water, the solubility of AR-A014418 in DMSO, the solubility of AR-A014418 in PBS buffer, the animal experiment (test) of AR-A014418, the cell expriment (test) of AR-A014418, the in vivo, in vitro and clinical trial test of AR-A014418, the EC50, IC50,and Affinity of AR-A014418.
References:
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