![]() |
产地 | 中国 |
品牌 | Chemstan |
货号 | LC-01 |
用途 | 中间体 |
包装规格 | 20mg |
纯度 | 98%% |
CAS编号 | 83602-39-5 |
是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体,主打中药对照品/标准品/天然植物有效单体,小分子化合物库,药物杂质。所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务。
Fields of Application :
A potent inhibitor of tumor promoting phorbol ester TPA/PMA and inhibitor of Ca2+/calmodulin dependent EF-2 phosphorylation
CAS Number: | 83602-39-5 |
Purity: | >98% |
Molecular Weight: | 1216.63 |
Molecular Formula: | C63H113N11O12 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
Synonyms: | |
Chemical Name: | (3S,6S,9S,12R,15S,18S,21R,24S,30S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,22,25,28-decamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17, |
Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Cyclosporin H is immunologically inactive. Does not bind to immunophilin. Cyclosporin H is a potent inhibitor of tumor promoting phorbol ester TPA/PMA in mouse skin . Potent inhibitor of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro. Potent and selective antagonist of FPR ( Formyl peptide receptor). Inhibits Formyl peptide-induced superoxide Formation.For the detailed information of Cyclosporin H, the solubility of Cyclosporin H in water, the solubility of Cyclosporin H in DMSO, the solubility of Cyclosporin H in PBS buffer, the animal experiment (test) of Cyclosporin H, the cell expriment (test) of Cyclosporin H, the in vivo, in vitro and clinical trial test of Cyclosporin H, the EC50, IC50,and Affinity of Cyclosporin H.
References:
CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C