|
| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 301836-43-1 |
| 是否进口 | 否 |
联合知名大学科研院所及企业开发药食两用植物标准品和天然植物有效单体，主打中药对照品/标准品/天然植物有效单体，小分子化合物库，药物杂质。所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。
| 常用名 | 4-[4-(2,3-二氢-1,4-苯并二氧杂环己-6-基)-5-(2-吡啶基)-1H-咪唑-2-基]苯甲酰胺 | 英文名 | D4476 |
|---|---|---|---|
| CAS号 | 301836-43-1 | 分子量 | 398.414 |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 675.0±55.0 °C at 760 mmHg |
| 分子式 | C23H18N4O3 | 熔点 | N/A |
| MSDS | 中文版 美版 | 闪点 | 362.0±31.5 °C |
D4476是具有有效性，选择性和细胞渗透性的CK1抑制剂，其在体外实验的IC50值为0.3 μM。
Fields of Application :
D4476, a cell-permeant inhibitor of CK1δ (IC90 <10 uM), suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a, D4476 originally identified as inhibitors of activin receptor-like kinase ALK5.
| CAS Number: | 301836-43-1 |
| Purity: | >98% |
| Molecular Weight: | 398.41402 |
| Molecular Formula: | C23H18N4O3 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | Casein Kinase I Inhibitor; D 4476; D-4476 |
| Chemical Name: | 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
For the detailed information of D4476 (D-4476), the solubility of D4476 (D-4476) in water, the solubility of D4476 (D-4476) in DMSO, the solubility of D4476 (D-4476) in PBS buffer, the animal experiment (test) of D4476 (D-4476), the cell expriment (test) of D4476 (D-4476), the in vivo, in vitro and clinical trial test of D4476 (D-4476), the EC50, IC50,and Affinity of D4476 (D-4476), Please contact DC Chemicals.
