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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 1219168-18-9 |
| 是否进口 | 否 |
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Fields of Application :
Dorsomorphin 2Hcl (Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; also inhibits ALK2, ALK3, and ALK 6 .
| CAS Number: | 1219168-18-9 |
| Purity: | >98% |
| Molecular Weight: | 472.41 |
| Molecular Formula: | C24H27Cl2N5O |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | BML-275; Compound C; BML275; BML 275 |
| Chemical Name: | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Dorsomorphin is a selective inhibitor of Bone morphogenetic protein (BMP) signaling. It has been found to inhibit BMP signals required For embryogenesis and promoted significant neural differentiation from human pluripotent stem cell (hPSC) lines. Dorsomorphin also acts as a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase); Ki = 109 nM in the presence of 5 μM ATP and the absence of AMP).For the detailed information of Dorsomorphin, the solubility of Dorsomorphin in water, the solubility of Dorsomorphin in DMSO, the solubility of Dorsomorphin in PBS buffer, the animal experiment (test) of Dorsomorphin, the cell expriment (test) of Dorsomorphin, the in vivo, in vitro and clinical trial test of Dorsomorphin, the EC50, IC50,and Affinity of Dorsomorphin.
References:
C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3.Cl.Cl
