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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途 | 中间体 |
| 包装规格 | 20mg |
| 纯度 | 98%% |
| CAS编号 | 202463-68-1 |
| 是否进口 | 否 |
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Fields of Application :
Potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM for CB1 and CB2 receptors respectively). Increases locomotor activity following systemic administration in vivo. Analog of SR141716A (Ki = 14 nM).
| CAS Number: | 202463-68-1 |
| Purity: | >98% |
| Molecular Weight: | 557.22 |
| Molecular Formula: | C21H19Cl2IN4O2 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | AM281,AM-281 |
| Chemical Name: | 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
Potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM For CB1 and CB2 receptors respectively). Increases locomotor activity following systemic administration in vivo. Analog of SR141716A (Ki = 14 nM).For the detailed information of AM 281, the solubility of AM 281 in water, the solubility of AM 281 in DMSO, the solubility of AM 281 in PBS buffer, the animal experiment (test) of AM 281, the cell expriment (test) of AM 281, the in vivo, in vitro and clinical trial test of AM 281, the EC50, IC50,and Affinity of AM 281.
References:
O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(I)C=C3)=C1C)NN4CCOCC4
