产品描述
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
靶点活性
ADCs Linker    Others 
别名
N-[6-(2,5-二氢-2,5-二氧代-1H-吡咯-1-基)-1-氧代己基]-L-缬氨酰-N5-(氨基甲酰基)-N-[4-(羟甲基)苯基]-L-鸟氨酰胺
纯度
98%
分子量
572.65
分子式
C28H40N6O7
CAS No.
159857-80-4
存储
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
溶解度
DMSO: 22 mg/mL (38.42 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
参考文献
1. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
Note
For research use only .