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牛磺熊去氧胆酸钠用途： 

Tauroursodeoxycholate Sodium是一种两亲性胆汁酸，有助于治疗*和胆囊问题。

Fields of Application : 
Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.

Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)

Note: Products for research use only, not for human use

Description:
In vitro, Tauroursodeoxycholate shows protective and reversing effects on 17βEG-induced impairment of the cVA-of-CLF. In Mz-ChA-1 cholangiocarcinoma cells, Tauroursodeoxycholate inhibits cell growth via Ca2+-, PKC-, and MAPK-dependent pathways. In isolated rat hepatocytes, Tauroursodeoxycholate inhibits bile acid-Induced Apoptosis via a β1-integrin-mediated formation of cAMP. In phalloidin-induced cholestasis rats, Tauroursodeoxycholate (360 μmol/kg, i.v.) significantly suppresses the decrease in bile flow and increases in serum alkaline phosphatase, leucine aminopeptidase and glutamic pyruvic transaminase activities, cholesterol, phospholipid and bile acid concentrations. For the detailed information of Sodium Tauroursodeoxycholate (TUDC), the solubility of Sodium Tauroursodeoxycholate (TUDC) in water, the solubility of Sodium Tauroursodeoxycholate (TUDC) in DMSO, the solubility of Sodium Tauroursodeoxycholate (TUDC) in PBS buffer, the animal experiment (test) of Sodium Tauroursodeoxycholate (TUDC), the cell expriment (test) of Sodium Tauroursodeoxycholate (TUDC), the in vivo, in vitro and clinical trial test of Sodium Tauroursodeoxycholate (TUDC), the EC50, IC50,and affinity,of Sodium Tauroursodeoxycholate (TUDC), For the detailed information of Sodium Tauroursodeoxycholate (TUDC), the solubility of Sodium Tauroursodeoxycholate (TUDC) in water, the solubility of Sodium Tauroursodeoxycholate (TUDC) in DMSO, the solubility of Sodium Tauroursodeoxycholate (TUDC) in PBS buffer, the animal experiment (test) of Sodium Tauroursodeoxycholate (TUDC), the cell expriment (test) of Sodium Tauroursodeoxycholate (TUDC), the in vivo, in vitro and clinical trial test of Sodium Tauroursodeoxycholate (TUDC), the EC50, IC50,and affinity,of Sodium Tauroursodeoxycholate (TUDC)