15926423062
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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | LC-01 |
| 用途范围 | 中间体 |
| 纯度 | 98%% |
| CAS编号 | 110683-10-8 |
| 规格 | 20mg |
| 是否进口 | 否 |
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| 常用名 | N-(对戊基肉桂酰基)* | 英文名 | N-(p-amylcinnamoyl) Anthranilic Acid |
|---|---|---|---|
| CAS号 | 110683-10-8 | 分子量 | 337.41 |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 563.1±50.0 °C at 760 mmHg |
| 分子式 | C21H23NO3 | 熔点 | N/A |
| MSDS | N/A | 闪点 | 294.4±30.1 °C |
Fields of Application :
ACA is a cell permeable inhibitor of PLA2,reported to inhibit α-ketoisocaproic acid and glyceraldehyde-induced insulin secretion, as well as glucose-induced insulin secretion.
| CAS Number: | 110683-10-8 |
| Purity: | >98% |
| Molecular Weight: | 337.4 |
| Molecular Formula: | C21H23NO3 |
Quality Control: HPLC、NMR、 LC/MS(Please contact us to get the QC report)
| Synonyms: | |
| Chemical Name: | |
| Storage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Note: Products for research use only, not for human use
Description:
N-(p-Amylcinnamoyl) anthranilic Acid (ACA), a cell permeable inhibitor of PLA2, has been reported to inhibit α-ketoisocaproic acid and glyceraldehyde-induced insulin secretion, as well as glucose-induced insulin secretion. Additionally, by inhibiting PLA2, ACA consequentially suppresses glucose-induced arachidonic acid formation in cells. Furthermore, research has shown ACA to modulate the activity of different transient receptor potential channels. In particular, ACA's blocking ability of diacylglycerol-activated TRP channels is of special interest since it offers the opportunity to interfere with receptor-induced Ca2+-dependent signaling processes in vascular smooth muscle cells and platelets.
References:
CCCCCC1=CC=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O
15926423062
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