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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | CS-N0036 |
| 用途 | 标准品 |
| 包装规格 | 5mg |
| 纯度 | 99.84%% |
| CAS编号 | 553-21-9 |
| 是否进口 | 否 |
| 描述 | Costunolide有抗炎和抗氧化活性，能介导凋亡。 |
|---|---|
| 相关类别 | 信号通路 >> 细胞凋亡 >> 细胞凋亡 研究领域 >> 癌症 天然产物 >> 萜类化合物和糖苷 |
| 参考文献 | [1]. Cheon YH, Song MJ, Kim JY, Costunolide Inhibits Osteoclast Differentiation by Suppressing c-Fos Transcriptional Activity. Phytother Res. 2013 Jul 6. [2]. Rasul A, Bao R, Malhi M, Induction of apoptosis by costunolide in bladder cancer cells is mediated through ROS generation and mitochondrial dysfunction. Molecules. 2013 Jan 24;18(2):1418-33. [3]. Kretschmer N, Rinner B, Stuendl N, Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expression in human soft tissue sarcoma cells. Planta Med. 2012 Nov;78(16):1749-56. [4]. Matsuda H, Shimoda H, Ninomiya K, Inhibitory mechanism of costunolide, a sesquiterpene lactone isolated from Laurus nobilis, on blood-ethanol elevation in rats: involvement of inhibition of gastric emptying and increase in gastric juice secretion. Alcohol Alcohol. 2002 Mar-Apr;37(2):121-7. |
