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产地 | 中国 |
品牌 | Chemstan |
货号 | CS-N0890 |
用途 | 标准品 |
包装规格 | 10mg |
纯度 | 98.03%% |
CAS编号 | 102040-03-9 |
是否进口 | 否 |
描述 | 土贝母苷甲(Tubeimoside I)是中药土贝母提取物,已被证明为人类各种癌症的一种有效的抗肿瘤剂。 |
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相关类别 | 信号通路 >> 其他 >> 其他 研究领域 >> 癌症 天然产物 >> 萜类化合物和糖苷 |
参考文献 | [1]. Wang Y, et al. Natural plant extract tubeimoside I promotes apoptosis-mediated cell death in cultured human hepatoma (HepG2) cells. Biol Pharm Bull. 2011;34(6):831-8. [2]. Xu Y, et al. Intrinsic apoptotic pathway and G2/M cell cycle arrest involved in tubeimoside I-induced EC109 cell death. Chin J Cancer Res. 2013 Jun;25(3):312-21. [3]. Wu Q, et al. Tubeimoside-1 attenuates LPS-induced inflammation in RAW 264.7 macrophages and mouse models. Immunopharmacol Immunotoxicol. 2013 Aug;35(4):514-23. [4]. Liu HZ, et al. Tubeimoside I sensitizes cisplatin in cisplatin-resistant human ovarian cancer cells (A2780/DDP) through down-regulation of ERK and up-regulation of p38 signaling pathways. Mol Med Rep. 2011 Sep-Oct;4(5):985-92. [5]. Chen WJ, et al. Tubeimoside-1 induces G2/M phase arrest and apoptosis in SKOV-3 cells through increase of intracellular Ca2+ and caspase-dependent signaling pathways. Int J Oncol. 2012 Feb;40(2):535-43. |