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产地 | 中国 |
品牌 | Chemstan |
货号 | CS-N0676 |
用途 | 标准品 |
包装规格 | 10mg |
纯度 | 98.00%% |
CAS编号 | 134418-28-3 |
是否进口 | 否 |
描述 | 脱水穿心莲内酯(Dehydroandrographolide)是从中草药穿心莲提取的天然化合物,具有抗感染活性。 |
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相关类别 | 信号通路 >> 抗感染 >> 流感病毒 天然产物 >> 萜类化合物和糖苷 研究领域 >> 感染 |
参考文献 | [1]. Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenous administration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6. [2]. Chao WW, et al. Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010 May 13;5:17. [3]. Basak A, et al. Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters. Biochem J. 1999 Feb 15;338 ( Pt 1):107-13. [4]. Zhu T, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41. [5]. Chen H, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9. |