去氧穿心莲内酯Deoxyandrographolide-武汉科斯坦生物科技有限公司

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去氧穿心莲内酯Deoxyandrographolide

品牌：Chemstan

产地：中国

货号：CS-N0857

cas：79233-15-1

价格： ￥2100/支
发布日期： 2020-11-26
更新日期： 2025-09-22

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产地	中国
品牌	Chemstan
货号	CS-N0857
用途	标准品
包装规格	5mg
纯度	98.00%%
CAS编号	79233-15-1
是否进口	否

描述	去氧穿心莲内酯 (Deoxyandrographolide) 是天然提取化合物，被报道有抗肝癌和胆管癌细胞(HuCCA-1和RMCCA-1细胞)。
相关类别	信号通路 >> 其他 >> 其他研究领域 >> 癌症天然产物 >> 萜类化合物和糖苷
参考文献	[1]. Mandal S, et al. 14-Deoxyandrographolide alleviates ethanol-induced hepatosteatosis through stimulation of AMP-activated protein kinase activity in rats. Alcohol. 2014 Mar;48(2):123-32. [2]. Roy DN, et al. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Br J Pharmacol. 2010 Aug;160(7):1823-43. [3]. Burgos RA, et al. 14-deoxyandrographolide as a platelet activating factor antagonist in bovine neutrophils. Planta Med. 2005 Jul;71(7):604-8. [4]. Mandal S, et al. 14-Deoxyandrographolide targets adenylate cyclase and prevents ethanol-induced liver injury through constitutive NOS dependent reduced redox signaling in rats. Food Chem Toxicol. 2013 Sep;59:236-48.

描述

去氧穿心莲内酯 (Deoxyandrographolide) 是天然提取化合物，被报道有抗肝癌和胆管癌细胞(HuCCA-1和RMCCA-1细胞)。

相关类别

信号通路 >> 其他 >> 其他

研究领域 >> 癌症

天然产物 >> 萜类化合物和糖苷

参考文献

[1]. Mandal S, et al. 14-Deoxyandrographolide alleviates ethanol-induced hepatosteatosis through stimulation of AMP-activated protein kinase activity in rats. Alcohol. 2014 Mar;48(2):123-32.

[2]. Roy DN, et al. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Br J Pharmacol. 2010 Aug;160(7):1823-43.

[3]. Burgos RA, et al. 14-deoxyandrographolide as a platelet activating factor antagonist in bovine neutrophils. Planta Med. 2005 Jul;71(7):604-8.

[4]. Mandal S, et al. 14-Deoxyandrographolide targets adenylate cyclase and prevents ethanol-induced liver injury through constitutive NOS dependent reduced redox signaling in rats. Food Chem Toxicol. 2013 Sep;59:236-48.