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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | CS-P1410A |
| 用途 | 分析检测 |
| 包装规格 | 500?μg |
| 纯度 | 99%% |
| CAS编号 | |
| 是否进口 | 否 |
GsMTx4 TFA 是一种蜘蛛毒液肽，选择性地抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透的机械敏感性通道 (MSCs)。GsMTx4 TFA 是一种重要的药理学工具，用于鉴定兴奋性 MSCs 在正常生理学和病理学中的作用。GsMTx4 TFA 显着减弱膀胱机能亢进。
| Description | GsMTx4 TFA is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology[1] . GsMTx4 TFA significantly attenuates bladder hyperactivity[2] . |
|---|---|
| IC50 & Target | MSCs[1] |
| Molecular Weight | 4215.91 |
| Formula | C???H???N??F?O??S? |
| Sequence | Gly-Cys-Leu-Glu-Phe-Trp-Trp-Lys-Cys-Asn-Pro-Asn-Asp-Asp-Lys-Cys-Cys-Arg-Pro-Lys-Leu-Lys-Cys-Ser-Lys-Leu-Phe-Lys-Leu-Cys-Asn-Phe-Ser-Phe |
| Sequence Shortening | GCLEFWWKCNPNDDKCCRPKLKCSKLFKLCNFSF |
| Shipping | Room temperature in continental US; may vary elsewhere. |
| Storage | Protect from light Powder-80°C2 years-20°C1 year *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Solvent & Solubility | In Vitro: H2O : 16.67 mg/mL (3.95 mM; Need ultrasonic) Preparing ConcentrationSolventMass1 mg5 mg10 mg1 mM0.2372 mL1.1860 mL2.3720 mL5 mM---------10 mM--------- * 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
| References |
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