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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | CS-P1923 |
| 用途 | 分析检测 |
| 包装规格 | 100mg |
| 纯度 | 99%% |
| CAS编号 | |
| 是否进口 | 否 |
| Description | L-Asparaginase (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis[1] . |
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| Clinical Trial | NCT NumberSponsorConditionStart DatePhaseNCT00526175PETHEMA FoundationAcute Lymphoblastic LeukemiaJune 2001Phase 4NCT01358253Ruijin HospitalAcute Lymphoblastic LeukemiaDecember 2010Phase 4NCT00098839Children′s Oncology Group|National Cancer Institute (NCI)Recurrent Childhood Acute Lymphoblastic LeukemiaFebruary 2005Phase 1|Phase 2 |
| CAS No. | 9015-68-3 |
| 中文名称 | L-天门冬酰胺酶 |
| Shipping | Room temperature in continental US; may vary elsewhere. |
| Storage | Protect from light Powder-80°C2 years-20°C1 year *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Solvent & Solubility | In Vitro: 0.1 M HCL : 50 mg/mL (ultrasonic and adjust pH to 3 with HCl) H2O : < 0.1 mg/mL (insoluble) |
| References |
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