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产地 | 中国 |
品牌 | Chemstan |
货号 | CS-P1923 |
用途 | 分析检测 |
包装规格 | 100mg |
纯度 | 99%% |
CAS编号 | |
是否进口 | 否 |
Description | L-Asparaginase (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis[1] . |
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Clinical Trial | NCT NumberSponsorConditionStart DatePhaseNCT00526175PETHEMA FoundationAcute Lymphoblastic LeukemiaJune 2001Phase 4NCT01358253Ruijin HospitalAcute Lymphoblastic LeukemiaDecember 2010Phase 4NCT00098839Children′s Oncology Group|National Cancer Institute (NCI)Recurrent Childhood Acute Lymphoblastic LeukemiaFebruary 2005Phase 1|Phase 2 |
CAS No. | 9015-68-3 |
中文名称 | L-天门冬酰胺酶 |
Shipping | Room temperature in continental US; may vary elsewhere. |
Storage | Protect from light Powder-80°C2 years-20°C1 year *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Solvent & Solubility | In Vitro: 0.1 M HCL : 50 mg/mL (ultrasonic and adjust pH to 3 with HCl) H2O : < 0.1 mg/mL (insoluble) |
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