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N-Boc-Phe-Leu-Phe-Leu-Phe
  • 品牌:Chemstan
  • 产地:中国
  • 货号:CS-P1795
  • cas:148182-34-7
  • 价格: ¥900/支
  • 发布日期: 2020-11-25
  • 更新日期: 2025-09-19
产品详请
产地 中国
品牌 Chemstan
货号 CS-P1795
用途 分析检测
包装规格 1mg
纯度 99%%
CAS编号 148182-34-7
是否进口

N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) 是一种甲酰肽受体 1?(FPR1)?拮抗剂,可增加疼痛作用并抑制膜联蛋白的抗疼痛活性。

Description

N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin[1] [2] .

IC50 & Target

FPR1[1]

Molecular Weight

785.97

Formula

C??H??N?O?

CAS No.

148182-34-7

Sequence

Boc-Phe-Leu-Phe-Leu-Phe

Sequence Shortening

Boc-FLFLF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder-80°C2 years-20°C1 yearIn solvent-80°C6 months-20°C1 month

Solvent & Solubility

In Vitro: 

H2O : < 0.1 mg/mL (insoluble)

References
  • [1]. Schepetkin IA, et al. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones. Biochem Pharmacol. 2014 Dec 15;92(4):627-41.

    [2]. Pei L, et al. Annexin 1 exerts anti-nociceptive effects after peripheral inflammatory pain through formyl-peptide-receptor-like 1 in rat dorsal root ganglion. Br J Anaesth. 2011 Dec;107(6):948-58.


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