Bradykinin B₁ receptor^[1]

[Des-Arg9]-Bradykinin acetate is a Bradykinin(B₁) receptor agonist. The B₂ receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B₁ receptor mediates the action of [Des-Arg⁹]-Bradykinin (des-Arg⁹-BK) and Lys-des-Arg Arg⁹-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

964.07

C??H??N??O??

23827-91-0

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe

RPPGFSPF

[Des-Arg9]-缓激肽醋酸盐

Room temperature in continental US; may vary elsewhere.

Powder-20°C3 yearsIn solvent-80°C6 months-20°C1 month

In Vitro: 

H₂O : 100 mg/mL (103.73 mM; Need ultrasonic)

Preparing
Stock Solutions

ConcentrationSolventMass1 mg5 mg10 mg1 mM1.0373 mL5.1863 mL10.3727 mL5 mM0.2075 mL1.0373 mL2.0745 mL10 mM0.1037 mL0.5186 mL1.0373 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

• [1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.