L-ANAP is a fluorescent, noncanonical amino acid which can be used for specific fluorescent labeling^[1] . L-ANAP is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa). Fluorescent Uaas, including L-dansylalanine, L-(7-hydroxycoumrin-4-yl)ethylglycine and L-ANAP, are of particular interest for molecular and cellular biology, which may complement and enchance the widely used fluorescent proteins (FPs)^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

308.76

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N[C@@H](CNC1=CC=C2C=C(C(C)=O)C=CC2=C1)C(O)=O.Cl

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

In Vitro: 

DMSO : 33.33 mg/mL (107.95 mM; Need ultrasonic)

H₂O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions

ConcentrationSolventMass1 mg5 mg10 mg1 mM3.2388 mL16.1938 mL32.3876 mL5 mM0.6478 mL3.2388 mL6.4775 mL10 mM0.3239 mL1.6194 mL3.2388 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

• [1]. Zagotta WN, et al. Measuring distances between TRPV1 and the plasma membrane using a noncanonical amino acid and transition metal ion FRET. J Gen Physiol. 2016 Feb;147(2):201-16.

  [2]. Xiang Z, et al. Enantiospecific synthesis of genetically encodable fluorescent unnatural amino acid L-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid. J Org Chem. 2011 Aug 5;76(15):6367-71.