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Parasin I (TFA)
  • 品牌:Chemstan
  • 产地:中国
  • 货号:CS-P0324A
  • 价格: ¥700/支
  • 发布日期: 2020-11-24
  • 更新日期: 2025-09-19
产品详请
产地 中国
品牌 Chemstan
货号 CS-P0324A
用途 分析检测
包装规格 500?μg
纯度 99%%
CAS编号
是否进口
Description

Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity[1] .

IC50 & Target

Bacterial[1]

Molecular Weight

2114.33

Formula

C??H???N??O??.C?HF?O?

Sequence

Lys-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Val-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser

Sequence Shortening

KGRGKQGGKVRAKAKTRSS

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder-80°C2 years-20°C1 yearIn solvent-80°C6 months-20°C1 month

Solvent & Solubility

In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

 ContentsAssign valueAcidic amino acidAsp (D), Glu (E), and the C-terminal -COOH.-1Basic amino acidArg (R), Lys (K), His (H), and the N-terminal -NH2+1Neutral amino acidGly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)0

3.  Recommended solution:

Overall charge of peptideDetailsNegative (<0)1.  Try to dissolve the peptide in water first.2.  If water fails, add NH4OH (<50 μL).3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.Positive (>0)1.  Try to dissolve the peptide in water first.2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.Zero (=0)1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

References
  • [1]. Koo YS, et al. Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides. 2008


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