产地 | 中国 |
品牌 | Chemstan |
货号 | CS-P1485A |
用途范围 | 分析检测 |
纯度 | 99%% |
规格 | 5mg |
是否进口 | 否 |
Substance P (1-7)(TFA) 是神经肽 P 物质 (SP) 的片段。Substance P (1-7)(TFA) 可对孤束核产生抑制和缓和作用。
Description | Substance P(1-7) TFA is a fragment of the neuropeptide, substance P (SP). Substance P(1-7) TFA gives depressor and bradycardic effects when applied to the nucleus tractus solitarius[1] . |
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In Vivo | Substance P(1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P(1-7) is an endogenous modulator of SP actions[1] . Injection of low doses of Substance P(1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord[2] . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
Molecular Weight | 1014.06 |
Formula | C??H??F?N??O?? |
Sequence | Arg-Pro-Lys-Pro-Gln-Gln-Phe |
Sequence Shortening | RPKPQQF |
Shipping | Room temperature in continental US; may vary elsewhere. |
Storage | Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month |
Solvent & Solubility | In Vitro: H2O : 50 mg/mL (49.31 mM; Need ultrasonic) Preparing ConcentrationSolventMass1 mg5 mg10 mg1 mM0.9861 mL4.9307 mL9.8613 mL5 mM0.1972 mL0.9861 mL1.9723 mL10 mM0.0986 mL0.4931 mL0.9861 mL * 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
References |
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