TAT peptide is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1^[1] . TAT peptide (GRKKRRQRRRPQ) functionalized hybrid nanoparticles are also studied due to their combined magnetic enrichment and optical detection for cell separation and rapid cell labelling. A cell viability assay reveals good biocompatibility of these hybrid nanoparticles^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1621.91

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Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Gln

GRKKRRQRRRPQ

Room temperature in continental US; may vary elsewhere.

Powder-80°C2 years-20°C1 yearIn solvent-80°C6 months-20°C1 month

In Vitro: 

H₂O : ≥ 25 mg/mL (15.41 mM)

* "≥" means soluble, but saturation unknown.

Preparing 
Stock Solutions

ConcentrationSolventMass1 mg5 mg10 mg1 mM0.6166 mL3.0828 mL6.1656 mL5 mM0.1233 mL0.6166 mL1.2331 mL10 mM0.0617 mL0.3083 mL0.6166 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

• [1]. Orzáez M, et al. Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells toerlotinib/cell-cycle inhibitors combination treatment. Cell Death Dis. 2012 Oct 25;3:e415.

  [2]. Lou L, et al. Functionalized magnetic-fluorescent hybrid nanoparticles for cell labelling. Nanoscale. 2011 May;3(5):2315-23.