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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | HY-P1759 |
| 用途 | 分析检测 |
| 包装规格 | 100mg |
| 纯度 | 99%% |
| CAS编号 | 65147-22-0 |
| 是否进口 | 否 |
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) 是一种组织蛋白酶底物，可用于评估溶酶体组织蛋白酶的活性。
| Description | [pThr3]-CDK5 Substrate TFA is an effective Phospho-Thr3CDK5 Substrate. [pThr3]-CDK5 Substrate is derived from the sequence of the histone H1 peptide that docks in the active site of CDK5. [pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 μM[1] . |
|---|---|
| Molecular Weight | 1332.45 |
| Formula | C??H???F?N??O??P |
| Sequence | Pro-Lys-{pTHR}-Pro-Lys-Lys-Ala-Lys-Lys-Leu |
| Sequence Shortening | PK-{pTHR}-PKKAKKL |
| Shipping | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Solvent & Solubility | In Vitro: H2O Peptide Solubility and Storage Guidelines: 1. Calculate the length of the peptide. 2. Calculate the overall charge of the entire peptide according to the following table: ContentsAssign valueAcidic amino acidAsp (D), Glu (E), and the C-terminal -COOH.-1Basic amino acidArg (R), Lys (K), His (H), and the N-terminal -NH2+1Neutral amino acidGly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)0 3. Recommended solution: Overall charge of peptideDetailsNegative (<0)1. Try to dissolve the peptide in water first.2. If water fails, add NH4OH (<50 μL).3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.Positive (>0)1. Try to dissolve the peptide in water first.2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.Zero (=0)1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration. |
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